- Two cases of Vessel invasion of Hepatocellular carcinoma
-
Sae Byeol Choi, Jae Yeon Seok, Kyung Sik Kim, Young Nyun Park, Kwang-Hyub Han, Jong Tae Lee
-
Journal of the Korean Liver Cancer Study Group. 2007;7(1):71-76. Published online June 30, 2007
-
-
-
Abstract
PDF
- Despite growing information on the clinical behavior of hepatocellular carcinoma(HCC), the histologic features
associated with survival are not well characterized. Several different staging systems are suggested for use in
predicting the prognosis of HCC. American Joint Committee on Cancer/International Union Against Cancer
Staging System (AJCC/UICC) 6th edition divided T stages according to vessel invasion, T1 without microvessel
invasion, T2 showing microvessel invasion and T3 showing major vessel invasion. The vessel invasion is
generally considered a poor prognostic factor for HCC. Our report of the two patients with HCC run along similar
terms. The patient diagnosed HCC with microvessel invasion underwent left lateral sectionectomy. Although the
presence of microvessel invasion was found, this patient has survived without any recurrence for over 5 years
now. The other patient underwent S8 segmentectomy and lived 10 years disease-free. After 10 years, although
an intrahepatic recurred HCC successfully treated with local therapy, the recurred and newly developed multiple
lesions were found again leading to a decision to perform operation. The HCC invaded into the portal vein and
constituted portal vein thrombosis. The patient expired after 3 months postoperatively due to intrahepatic
dissemination of the tumor. Therefore the impact of the vascular invasion on long-term survivors remains to be
determined.
|